TLR2 and injury: Recently it was shown that IL-1 and other pro-inflammatory cytokines may support neuronal survival [95]–[97] and that inflammatory stimulation induced either by lens injury [13], [15], [98], intravitreal injections of Zymozan [17], [99], crystallins [100] or toll-like receptors 2 agonists [101] transforms RGC into a regenerative state, enabling these neurons to survive and grow axons over the inhibitory environment of the injured optic nerve.