VEGFD and lymphangioleiomyomatosis: Interestingly, serum levels of VEGF-D were lower in LAM subjects (VEGF-D 1937±520 pg/mL) with lesser PGE2 compared to LAM subjects (VEGF-D 7298±2529 pg/mL) with higher PGE2, indicative of a strong correlation between PGE2 and VEGF-D (p<0.05, Figure 2E).