It has been proposed that the CP contributes to the production of cytokines during inflammatory events in the CNS [24], and studies with primary porcine choroid plexus cells (PCPEC) have shown that infection with Streptococcus suis (S. suis) induces production of cytokines and chemokines including IL8, IL6, and TNFα [25]. The gene discussed is CXCL8; the disease is infection.