The CFS was also used to prospectively identify immunodominant DR1 epitopes from HA1 protein of influenza A/Vietnam/1203/2004 (H5N1) and LSA-NRC, a recombinant modified version of a protein expressed exclusively in malaria-infected hepatocytes at a preerythrocytic stage, which was designed as a vaccine against preerythrocytic stage malaria. The gene discussed is DR1; the disease is malaria.