The decrease in Kindlin-3 protein expression within the subcutaneous tumors was confirmed by immunohistochemical analyses of the tumor sections (Figure 7A c) and by transcript quantification, which also show that Kindlin-3shRNA did not alter the expression of Kindlin-1 and Kindlin-2 in the tumor (Figure 7A d). The gene discussed is FERMT2; the disease is neoplasm.