In fact, a study to determine if Axl participates in the onset or the progression of CML became a study of noninsulin-dependent diabetes mellitus (NIDDM), when ectopic overexpression of Axl in the myeloid lineage of transgenic mice induced a NIDDM phenotype rather than causing hematopoietic malignancies [81]. Here, AXL is linked to type 2 diabetes mellitus.