TP53 and ductal breast carcinoma in situ: There were no significant associations between protein expression of CXCL1 among DCIS and IDC stromal tissues with: tumor size, BCL2 expression, P53 status, ER, PR, HER2 status, EGFR expression, lymph node status, Ki67 expression or age, which is also recognized as a prognostic factor [57, 58] (Table 2).