BCL2 and cervical cancer: To elucidate whether T. vaginalis metalloproteinases are involved in apoptosis in human cervical cancer cell line and immortalized human vaginal epithelial cell line and to evaluate the roles of the Bcl-2 family of proteins in T. vaginalis-induced apoptosis, we treated SiHa cells and MS74 cells with live T. vaginalis, T. vaginalis excretory and secretory products (ESP), T. vaginalis lysate with or without 1,10-phenanthroline (1,10-PT).