TMEM43 and arrhythmogenic right ventricular cardiomyopathy: A heterozygous TMEM43 gene mutation causes the type 5 autosomal dominant form of arrhythmogenic right ventricular cardiomyopathy (ARVC) identified in a founder population on the island province of Newfoundland in Canada [2], but is being increasingly identified in other populations, and may have been imported from continental Europe.