However, expression of E-cadherin and the EMT inducing transcription factors snail and slug were not altered Activin B expression (I. Wacker unpublished observations) suggesting that the standard EMT program is not induced by Activin B. Notably, cell scattering and induction of invasiveness by Rho-Kinase inhibitor in MCF7 breast tumor cells was shown to be similarly independent of EMT [41]. The gene discussed is SNAI2; the disease is breast neoplasm.