DSPP and deafness: We identified many well-established deafness mutations (e.g., GJB2 c.235delC, GJB2 p.V37I, SLC26A4 c.919-2A > G [12], as well as previously un-reported novel mutations (e.g., DSPP c.3264_3265insCGATAGCGG, p.S1088delinsSRX) which we predict to be deleterious to protein functioning.