Table 1 presents the urine NGAL levels of patients with or without clinical AKI, and shows that the level increased significantly at 12 h postsurgery in patients with AKI compared with that in patients without AKI.The area under the ROC curve of urine NGAL-12 h for predicting clinical AKI was 0.886 (95% CI 0.803-0.969, p <0.001; cutoff 92.85 ng/mL, sensitivity 77.8%, and specificity 80.4%; Figure 1). This evidence concerns the gene LCN2 and acute kidney injury.