TP63 and posterior cortical atrophy: The transcription factor p63 is specifically expressed in prostate basal epithelial cells21,51, 52, 53 and altered p63 expression is utilised in PCa diagnosis.20,21,23,54,55 A ‘Prostate-63 Cancer Diagnostic Test' has been approved by the US Food and Drug Administration (FDA) as a diagnostic marker of PCa in clinical samples.