In further studies based on the same CRC patients, we found mRNA and the AC133 protein epitope expression of Prominin-1/CD133, a marker associated with stemness and poor prognosis in several solid tumors, to be downregulated, including some additional stem cell-related genes, which belonged to the families of WNTs and bone morphogenetic proteins (BMPs) (8–10). Here, PROM1 is linked to colorectal carcinoma.