Moreover, C. elegans responds to infections using an inducible innate immune system that is controlled by several evolutionary conserved signaling cascades including the p38-MAPK (PMK-1), insulin-IGF (DAF-16), GATA (ELT-2), and TGF-B (SMA-6) pathways [5]–[8]. The gene discussed is QRSL1; the disease is infection.