Since proinflammatory macrophages are important in the pathogenic process in RA and there is no data on the expression and function of the inhibitory FcγR on such macrophages we aimed to delineate the expression of FcγR receptors on homeostatic M-CSF macrophages (mMφ) and inflammatory GM-CSF macrophages (gmMφ). Here, FCGR2A is linked to rheumatoid arthritis.