Moreover, blast-injury in Elk-1 KO group resulted in significantly less thigmotaxis compared to blast injured WTLM, suggesting a possible role for Elk-1 in post-traumatic anxiety (0.626 ± 0.028 Elk+blast vs. 0.820 ± 0.033 WTLM+blast, p = 0.0081). This evidence concerns the gene ELK1 and Anxiety.