Many lncRNAs have been mapped at cancer risk loci in the human genome, such as PTCSC3 (14q13.3) in thyroid cancer (45,46), PCA3 (9q21–22) in prostate cancer (47,48), ANRIL (9p21) in prostate and breast cancers, leukemia and melanoma (49–52), MALAT1 (11q13) in liver, colorectal, prostate, bladder and lung cancers (53–56). Here, MALAT1 is linked to Familial prostate cancer.