In addition, the pattern of chemokine gene regulation observed in the systemic organs (spleen and kidney) seems to be specific for different viral infections [46], with a VHSV-specific pattern that includes CK1, CK3, CK5B, CK6, CK12, CXCL11_L1 and CXCL-F1 up-regulation. This evidence concerns the gene KRT12 and viral infectious disease.