Recently, an investigation, regarding IFIH1 rs1990760 associated with susceptibility to SLE and PM/DM, was performed in the Japanese population, which suggested IFIH1 rs1990760 polymorphism was not significantly associated with PM/DM as a whole in this study, but only showed the AA genotype tended to be found with higher frequency in the PM with ILD subset. This evidence concerns the gene IFIH1 and systemic lupus erythematosus.