Therefore, in this study, we evaluated the effect of a novel aminothiazole inhibitor of TNIK, 5-(4-methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide (hereinafter referred to as our database code number, KY-05009; Fig. 1A), on TGF-β-mediated EMT in human lung adenocarcinoma A549 cells [23]. This evidence concerns the gene TNIK and lung adenocarcinoma.