CYP24A1 gene expression was evaluated in 13 human melanoma lines in comparison to second passages of human epidermal melanocytes from neonatuses (HEMn) and human epidermal melanocytes from adult (HEMa), and kuman epidermal keratinocytes from neonatuses (HEKn), human epidermal keratinocytes from adults (HEKa) and immortalized HaCaT epidermal keratinocytes (Table 1). This evidence concerns the gene CYP24A1 and melanoma.