Wild-type p53-induced phosphatase 1 (Wip1 or PPM1D) is involved in DNA repair and cell cycle checkpoint pathways and Wip1 is frequently amplified or overexpressed in different human cancers, promoting tumor growth by switching off major checkpoint kinases and p53 [10], [17], [18], [19], [20]. This evidence concerns the gene PPM1D and neoplasm.