SOD2 and breast cancer: Additionally, an inverse relationship between GILT expression and Ki67 index, a proliferation marker for breast cancer [24], is in agreement with the cell proliferation inhibiting role of GILT in fibroblasts [25], which functions by affecting activity and stability of superoxide dismutase (SOD2), and consequently affects the levels of reactive oxygen radicals (ROS) and ERK1/2 phosphorylation [25], [26], [27].