Therefore, we tried to assess the impact of FGFR2 intron 2 polymorphisms (rs2981582, rs1219648, rs2981578 and rs7895676) on sporadic breast cancer and determined their association with the risk for North Indian women in a case control approach, including combined effect of these variants, LD structure measurement, haplotype analysis, as well as relation with patients' clinical, environmental and lifestyle characteristics. Here, FGFR2 is linked to breast cancer.