Furthermore, disease alleles were observed for other autosomal dominantly inherited degenerative diseases of sensory function, including retinitis pigmentosa (SEMA4A, RP1), deafness (MYO1A), glaucoma (CYP1B1, OPTN, WDR36), and keratoconus (VSX1). The gene discussed is OPTN; the disease is keratoconus.