PXK and systemic lupus erythematosus: This locus has been previously reported in a SLE GWAS [29] and meta-analysis [32], however the peak associations were reported for SNPs in the nearby gene PXK. While the PXK and DNASE1L3 associations may be independent, no SNPs on the Illumina HumanHap300 chip used in the SLE GWAS are good tags for the missense SNP in DNASE1L3 (maximum r2 of 0.21).