TRIM63 and hydrops fetalis: The present finding that aerobic ET performed during the transition from cardiac dysfunction to HF prevents the overactivation of some proteasomal components is similar to that of Gielen et al. [59] that observed a attenuation of MuRF1 by exercise training and Campos et al. [6], who also observed a reduction of ubiquitin-proteasome system activation in response to ET.