KEGG pathway analysis (Table S5) of the 63 miRNA dataset suggests that these EV miRNAs may modulate several genes associated with signalling pathways in recipient cells – these include important pathways implicated in cancer such as the Wnt, Ras, TGF-β, and p53 signalling pathways [73], [74], [75]. Here, TGFB1 is linked to cancer.