PRKAA1 and colorectal carcinoma: It is thought that miRs-19a/b are induced by Myc, and regulate cell survival by targeting the expression of PTEN [20], Bcl2L11, Prkaa1 and PP2A [64]; both miRs-19a/b have been observed in CRC patient tissue and blood and reported to be potential biomarkers for this disease [42], [65].