Ten out of 180 up-regulated genes were HOX/Homeobox genes, the majority of which were antennapedia- like homeobox- containing HOXB (B2, B3, B5, B6, B7) and MEOX2 genes along with the engrailed homeobox family gene EN1 and the zinc finger homeobox 1b ZEB2, mutations in which are associated with Mowat-Wilson syndrome [18]. The gene discussed is ZEB2; the disease is Mowat-Wilson syndrome.