The progression of insulin resistance contributes to the pathogenesis of NAFLD.10 In our results, many of the SM species containing saturated acyl chains positively correlated with the parameters of liver function (aspartate aminotransferase, alanine aminotransferase, γ-GTP and ChE levels, Table 3), suggesting that the increase in the levels of these SM species is related to the pathogenesis of NAFLD. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.