ATG7 and neoplasm: In studies following up on the role of the Ras pathway in tumor promotion and its dependence on autophagy, Strohecker et al. investigated whether pulmonar carcinogenesis driven by an activating B-Raf mutation was dependent on autophagy. Atg7 deletion increased oxidative stress and enhanced tumor growth at early stages, but promoted abnormal mitochondria accumulation, proliferation defects, a decrease in tumor burden, and increased survival of animals in more advanced stages of tumorigenesis.