TP53 and serous adenocarcinoma: Type I tumours (that include low-grade serous carcinoma, low-grade endometrioid carcinoma, clear cell carcinoma, mucinous carcinoma and Brenner tumour) usually have an indolent clinical behaviour, are often detected in early stage, rarely harbour p53 gene mutations, and are genetically stable, but each histological type has a distinct molecular profile, with mutations of genes involved in different signalling transduction pathways.