NFKB1 and cancer: Amongst them, 10 major pathways had important functions associated with cell proliferation, apoptosis, migration, and cell-cycle progression including pathways in cancer, MAPK signaling, NF-κB, T cell receptor and chemokine signaling, focal adhesion, adherens junction, cell adhesion molecules (CAMs), cell cycle and Wnt signaling pathway intermediates (P < 0.01) (Fig. 4C, S Table 1).