PTK2 and breast carcinoma: The recent study found that LVI was significantly associated with predicting patient outcome leading to shorter breast cancer specific survival as well as distant metastasis-free survival [27].Interestingly, we detected high level of FAK in metastatic samples with the median score FAK staining equal to 2.67, which was lower than in primary tumors (median score in 117 primary tumors was 3.5 (Figure 3).