SLC2A1 and neoplasm: The tumor tissues’ extra requirements of glucose, an essential nutrient for CSC that, when present in the culture environment, significantly increases the percentage of CSC-like cells in the overall cancer cell population (128), can be achieved via the epigenetic silencing of DERL3, the gene responsible for degrading the glucose transporter SLC2A1 [glucose transporter 1 (GLUT1)] (129).