XPC and Fanconi anemia: Tumors showed overrepresentation and overexpression of genes of all the DNA repair pathways, including the NER, BER, HR, MMR, and NHEJ, as well as the Fanconi anemia, all known to play a role in platinum resistance, while in normal lung only one DNA repair gene was overexpressed, the XPC in NER (Figure 7) (7, 53).