The top five genes were all overexpressed, namely the ISL1 (AUC = 1.00), HMGN2, CDKN2C, STMN1, and ACYP1. The GO of the differentially expressed genes of SCLC included mitotic cell cycle and DNA repair, while regulation of several metabolic processes was underrepresented. Here, ISL1 is linked to small cell lung carcinoma.