IFNG and infection: Priming with the FI-RSV vaccine or with RSV G-protein expressed in recombinant vaccinia virus, leads to enhanced Th2 driven inflammation upon re-infection (138–140) and infection in IFNγ deficient mice or depletion of NK cells, a primary source of IFNγ, leads to generation of type-2 inflammation to RSV infection (74, 141).