NRG1 and schizophrenia: Interestingly partial genetic deletion of Nrg1 hypophosphorylates NR2B subunits of NMDARs (Bjarnadottir et al., 2007) and promotes subtle changes in NMDAR binding in a number of schizophrenia relevant brain regions in adult rodents (Dean et al., 2008; Long et al., 2013; Newell et al., 2013).