The IAP proteins, XIAP and survivin, were detected in almost all the cells tested; XIAP was highly expressed in all the 12 cell lines tested and survivin was also overexpressed in 8 out of the 12 NSCLC cell lines, confirming their tumorigenic effect in previous reports,1,3 although immortalized lung cell line, Beas2B, also expressed high level of survivin (Figure 1b). This evidence concerns the gene XIAP and non-small cell lung carcinoma.