Glucose uptake is the first essential step in glucose metabolism and can be limiting in lymphocyte proliferation.19, 20, 21 Measurement of Glut family members in BCR-Abl+ murine B-ALL found expression of Glut1, Glut3, Glut6, Glut8, and Glut9, whereas the remaining Glut family members were undetected (Figure 1c). This evidence concerns the gene SLC2A1 and precursor B-cell acute lymphoblastic leukemia.