ABL1 and precursor B-cell acute lymphoblastic leukemia: To genetically target B-ALL glucose uptake, therefore, we generated primary BCR-Abl B-ALL cells from Glut1fl/fl/Ubi-Cre-ERT2 mice to enable inducible deletion of glucose transporter Glut1 upon treatment with 4-hydroxytamoxifen (4-OHT).