Myocardial infarction was diagnosed when 2 of the following criteria were met: significant ST-T changes, an increase in the cardiac biomarkers [Creatine phosphokinase-MB (CPK-MB) and cardiac Troponin I], and new myocardial wall motion abnormality seen on echocardiography. This evidence concerns the gene PIK3C2A and myocardial infarction.