On the other hand, CD45-CD34+ cell count in the peripheral blood was negatively associated with T2DM (r= -0.614; P<0.001), SUA (r=-0.466; P<0.001), hypertension (r=-0.240; P=0.026), the NT-pro-BNP level (r=-0.605; P=0.002), eGFR (r=-0.423; P=0.012), active smoking (r=-0.222; P=0.040). Here, NPPB is linked to type 2 diabetes mellitus.