GATA2 and GATA1 are implicated at many (up to 90%) of the TAL1-bound sites in normal hematopoietic cells, and GATA3 (Ono et al. 1998) along with ETS1 and RUNX1 (Palii et al. 2011) can direct TAL1 binding when it is aberrantly expressed in T-cell leukemias. This evidence concerns the gene RUNX1 and T-cell leukemia.