GATA2 and GATA1 are implicated at many (up to 90%) of the TAL1-bound sites in normal hematopoietic cells, and GATA3 (Ono et al. 1998) along with ETS1 and RUNX1 (Palii et al. 2011) can direct TAL1 binding when it is aberrantly expressed in T-cell leukemias. Here, GATA1 is linked to T-cell leukemia.