UGT1A1 and Hyperbilirubinemia: In consideration of the previously reported literatures and our report, we considered that exons 1 and 5 probably were hotspot regions of the UGT1A1 gene in Asian populations especially in Japanese and Chinese and p.G71R and p.Y486D were two most common variants leading to UGT1A1 genetically-associated unconjugated hyperbilirubinemia.