Recently, a placebo-controlled, randomized trial of MSC treatment in patients with moderate-to-severe COPD was published; after the infusion of allogeneic MSCs in COPD patients, no deaths, toxicity, or serious adverse reactions related to the MSC therapy occurred, but the circulating levels of C-reactive protein in the patients were markedly decreased [26]. Here, CRP is linked to chronic obstructive pulmonary disease.