Watanabe et al. found no mitotic figures in 7 of 38 small biopsies of LCNECs, and 11 of 38 small biopsies had inadequate tumor volume for mitotic count (<10 HPF); nevertheless, a Ki-67 index could adequately be assessed in all biopsies, and it was found to be in a range of 42-99% [24]. This evidence concerns the gene MKI67 and neoplasm.