This property of IKr/hERG has clinical significance as, on the one hand, hypokalemia can exacerbate effects of QT interval prolonging, hERG‐blocking drugs (Hancox et al. 2008) whilst, on the other hand, potassium supplementation has been reported to improve repolarization in some LQT2 patients (Compton et al. 1996; Etheridge et al. 2003). Here, KCNH2 is linked to Hypokalemia.