It was subsequently shown to also be a GWAS hit across several disorders (Cross Disorder Group of the Psychiatric Genomics Consortium, 2013a) and significant for schizophrenia alone, along with CACNB2 (encoding the Cavβ2 subunit) and other genes involved in calcium regulation (Ripke et al., 2013; Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2014). The gene discussed is CACNB2; the disease is schizophrenia.