For example, Kaspar et al. related the locus of dystrophin gene mutation to the timing of cardiomyopathy onset, with an early onset for deletions affecting the amino-terminal domain (exons 2 to 9) and a later onset for deletions removing part of the central rod domain and hinge 3 (exons 50 and/or 51) [6]. Here, DMD is linked to cardiomyopathy.